This time-released vitamin B3 supplement produces a number of beneficial effects to counteract the atherosclerotic process. It reduces the production of LDL in the liver and increases the production of beneficial HDL, which draws cholesterol away from the lining of the arteries. It removes triglycerides from the blood and appears to have a strong effect of prostaglandins. Niacin also dilates the blood vessels, which improves circulation and helps flush out existing plaque. It also supports tissue health in the gastrointestinal tract, nerves, and skin.